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New machine learning model to improve quality of life of cancer patients

The strong pharmaceuticals used by medical professionals to shrink the tumor cause side effects in patients despite administrating maximum safe doses.


Devdiscourse News Desk Last Updated at 12-08-2018 20:40:16 IST
New machine learning model to improve quality of life of cancer patients
  • For each patient, the model conducted about 20,000 trial-and-error test runs. (Image Credit: Wikimedia)

The quality of life of patients suffering from the Glioblastoma tumor, the most aggressive form of cancer may be improved with the new Artificial Intelligence (AI) system that is developed by MIT researchers.

The strong pharmaceuticals used by medical professionals to shrink the tumor cause side effects in patients despite administrating maximum safe doses.

The model developed by MIT researchers uses machine learning to look at treatment regimes currently in use and adjusts the doses. In simulated trials of 50 patients, the machine-learning model designed treatment cycles that reduced the potency to a quarter or half of nearly all the doses while maintaining the same tumor-shrinking potential.

For each patient, the model conducted about 20,000 trial-and-error test runs. Once training was complete, the model learned parameters for optimal regimens.

The researchers' model uses a technique called reinforced learning (RL), a method inspired by behavioral psychology, in which a model learns to favor certain behavior that leads to the desired outcome.

"We kept the goal, where we have to help patients by reducing tumor sizes but, at the same time, we want to make sure the quality of life - the dosing toxicity - doesn't lead to overwhelming sickness and harmful side effects," said Pratik Shah, from MIT.

(With inputs from PTI)


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