Union Minister of Agriculture & Farmers Welfare Shri Radha Mohan Singh today released recombinant Enzyme-linked immune sorbent assay (ELISA) kits: one for Glanders and other for Equine Infectious Anaemia. Both these diseases are notifiable diseases in India and require a special diagnosis for control and eradication in the country. Glanders is a fatal infectious and notifiable disease of equines including horses, donkeys and mules.
The disease is caused by a bacterium known as Burkholderia mallei and has zoonotic potential. The organism is also considered as potential bio-weapon and categorized under 'Tier 1 Select Agent'. After continuous research efforts of more than eight years, National Research Centre on Equines (NRCE) has been able to develop a recombinant Hcp1 antigen ELISA as an alternate to complement-fixation test (CFT). The ELISA has been duly validated in India and the OIE Reference Laboratory, Germany and showed excellent sensitivity (97.2%) and specificity (99.6%). This technology has been transferred to eight State Disease Diagnostic Laboratories following approval of DADF, Ministry of Agriculture & Family Welfare and commercialized for transformation into ready to use kit. This ELISA has a huge potential of international commercialization as recombinant protein-based ELISA is not available in any other country. This technology will prove to be a milestone in the control and eradication of glanders from India.
Equine infectious anaemia (EIA) is a chronic, debilitating and persistent infectious disease of equines caused by a retrovirus. It is an OIE notifiable disease. NRCE has also developed recombinant p26 protein-based ELISA as an alternative to Coggin's test. This technology will provide a sustainable and homogeneous source of antigen and harmonized protocol to ensure regular surveillance of EIA. Both kits are highly economical as compare to imported kits.
Minister of Agriculture & Farmers Welfare also released Technology Bulletin, NRCE Profile and Research Outcome of NRCE, Ministers of State Agriculture & Farmers Welfare, Smt. Krishna Raj was also present on this occasion.
(With Inputs from PIB)