Pioneering Trial Reveals Medication's Role in Reducing Domestic Violence

A groundbreaking trial by the University of New South Wales and University of Newcastle examined whether the antidepressant sertraline could curb domestic violence by improving impulse control in men. The study found significant reductions in domestic violence reoffending when paired with comprehensive psychosocial support.


Devdiscourse News Desk | Sydney | Updated: 07-12-2025 13:27 IST | Created: 07-12-2025 13:27 IST
Pioneering Trial Reveals Medication's Role in Reducing Domestic Violence
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  • Country:
  • Australia

In a world-first trial, researchers from the University of New South Wales and the University of Newcastle explored whether the antidepressant sertraline could help reduce domestic violence. Prime Minister Anthony Albanese has labeled domestic violence a national crisis, seeking solutions focused on prevention and perpetrators.

The trial involved 1,738 men screened between 2013 and 2021. Of the participants, 630 were randomized to receive either sertraline or a placebo. Results indicated a promising reduction in domestic violence reoffending among those who received the medication, with significant impacts seen at both 12 and 24 months of treatment.

Participants receiving comprehensive support alongside medication showed the best outcomes, highlighting the importance of addressing trauma and social disadvantages. With partners reporting improved safety and behavioral changes, this study presents a cost-effective and scalable intervention in the fight against domestic violence.

(With inputs from agencies.)

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