FACTBOX-Latest on the worldwide spread of the coronavirus

Europe, criticized by the World Health Organization over its slow rollout of vaccinations against COVID-19, is scrambling to speed up the pace of injections and avoid being left further behind by Britain and the United States. DEATHS AND INFECTIONS

* Eikon users, see COVID-19: MacroVitals https://apac1.apps.cp.thomsonreuters.com/cms/?navid=1592404098 for a case tracker and summary of the news. EUROPE

* Russia has agreements with 20 manufacturers in 10 countries worldwide to produce its Sputnik V COVID-19 vaccine, Kirill Dmitriev, head of the Russian Direct Investment Fund that markets the shot internationally, said. * More than 70 British lawmakers have signaled their opposition to the introduction of so-called vaccine passports that the government is considering introducing to help open the economy as it starts lifting restrictions.

* New restrictions in France will impact economic growth in 2021 but it is too early to say by how much, Finance Minister Bruno Le Maire said, as the country heads into its third lockdown. * Bulgaria will receive more than 1.2 million additional doses from Pfizer and BioNTech in the second quarter, Prime Minister Boyko Borissov said.

AMERICAS * Brazil's Sao Paulo sped up efforts to empty old graves and make room for a soaring number of COVID-19 deaths as the city hall registered record daily burials this week.

* The United States may not need AstraZeneca's vaccine, even if it wins U.S. regulatory approval, the nation's top infectious disease doctor Anthony Fauci said on Thursday. ASIA-PACIFIC

* The Philippines reported a daily record of 15,310 new coronavirus infections, one of the highest reported in the region since the pandemic started, bringing the country's total to 771,497 cases. * Authorities in the Japanese city of Osaka will discuss plans with the 2020 Tokyo Games organizers to cancel the western region's leg of the Olympic torch relay, its governor said, to avert a clash with measures to curb infections.

* Japan will also receive bigger shipments of Pfizer's vaccines to immunize the elderly faster, the government said after negotiating the increase in supplies. * India's temporary pause on major exports of AstraZeneca's shot could have a "catastrophic" impact if extended, the head of the continent's disease control body said on Thursday, before the country hit a six-month high in its tally of daily infections.

MIDDLE EAST AND AFRICA * Turkey began administering Pfizer and BioNTech's COVID-19 shots, introducing the second vaccine in its campaign that began in mid-January, as new cases reached record highs.

MEDICAL DEVELOPMENTS * The U.S. drug regulator gave Moderna clearance to speed up the output of its vaccine by letting it fill a single vial with up to 15 doses, with the United States banking on rapid immunization to stem the spread of the virus.

* South Africa's health regulator approved on Thursday Johnson & Johnson's vaccine, paving the way for large-scale deliveries of the shot the government has put at the heart of its immunization plans. ECONOMIC IMPACT

* Asian markets were set to open higher in a holiday-lightened trading session, riding a surge of strong factory data and falling bold yields that pushed U.S. and European benchmark stock indexes to record highs. (Compiled by Federico Maccioni and Juliette Portala; Editing by Gareth Jones and Barbara Lewis)