FACTBOX-Latest on the worldwide spread of the coronavirus

* Three-quarters of the people in Latin America and the Caribbean have not been fully immunised against COVID-19 in contrast to the United States and Canada, the Pan American Health Organization said on Wednesday. MIDDLE EAST AND AFRICA * An arrangement has been suspended whereby Johnson & Johnson was shipping vaccine doses to Europe that had been packaged in South Africa. * Abu Dhabi will remove the need to quarantine for all vaccinated travellers arriving from international destinations starting Sunday.

The United States plans to invest $3 billion in the vaccine supply chain as it continues to work to position itself as a leading supplier of vaccines for the world, a top health official said. DEATHS AND INFECTIONS

* Eikon users, see COVID-19: MacroVitals https://apac1.apps.cp.thomsonreuters.com/cms/?navid=1592404098 for a case tracker and summary of news EUROPE

* Italy may eventually make COVID-19 inoculations compulsory for everyone of eligible age, and plans to start administering booster vaccine shots later this month to vulnerable people, Prime Minister Mario Draghi said. * Twelve million French children, who returned to school from their summer break, wearing masks, were told by head teachers and President Emmanuel Macron that they should get vaccinated against COVID-19.

* Greece offered unvaccinated health care workers a second chance to get a shot against COVID-19 and allow those who have been already suspended to return to work as hundreds of them protested against mandatory vaccination. * Belgium's King Philippe and Queen Mathilde cancelled their attendance at all public events from Thursday after a family member tested positive for COVID-19.

ASIA-PACIFIC * Vietnam could face a lengthy battle against the coronavirus and cannot rely on lockdown and quarantine measures indefinitely, its prime minister said.

* India would resume exports of COVID-19 vaccines only after its own interests are taken care of, a health ministry official said, as a recent surge in immunisations raised hopes of foreign sales that have been barred since mid-April. AMERICAS

* Runners in this year's Boston Marathon will need to provide proof of vaccination or produce a negative COVID-19 test in order to participate. * Three-quarters of the people in Latin America and the Caribbean have not been fully immunised against COVID-19 in contrast to the United States and Canada, the Pan American Health Organization said on Wednesday.

MIDDLE EAST AND AFRICA * An arrangement has been suspended whereby Johnson & Johnson was shipping vaccine doses to Europe that had been packaged in South Africa.

* Abu Dhabi will remove the need to quarantine for all vaccinated travellers arriving from international destinations starting Sunday. MEDICAL DEVELOPMENTS

* Aspen Pharmacare said it was in talks to make J&J's shot under licence in South Africa, at what would be the continent's first major independent distribution base for a global vaccine against COVID-19. ECONOMIC IMPACT

* Record-setting world stocks moved higher after jobless claims data suggested the U.S. labor market was charging ahead even as new COVID-19 infections surge, while the risk of a upcoming sub-par U.S. payrolls report weighed on the dollar. * The World Trade Organization needs results by the end of the year and must focus its efforts on finding a global response to the pandemic, its director-general said.

* The roll-out of vaccinations is making life insurers more enthusiastic about offering coverage to those with underlying health conditions. (Compiled by Aditya Soni; Editing by Sriraj Kalluvila)