DBT-BIRAC facilitates establishment of mRNA vaccine candidate for COVID 19

DBT has provided seed funding for the development of Gennova’s novel self-amplifying mRNA-based vaccine candidate for COVID19.

DBT-BIRAC has facilitated the establishment of ‘first-of-its-kind’ mRNA-based vaccine manufacturing platform in India. DBT has provided seed funding for the development of Gennova’s novel self-amplifying mRNA-based vaccine candidate for COVID19.

In collaboration with HDT Biotech Corporation, Seattle, USA, Gennova has developed an mRNA vaccine candidate (HGCO19), with demonstrated safety, immunogenicity, neutralization antibody activity in the rodent and non-human primate models. The company is working aggressively to ensure first human injection by the end of the year, subject to Indian regulatory approvals.

Dr Renu Swarup, Secretary, DBT and Chairperson, BIRAC, speaking on the subject said that “diseases emanating from unknown and new pathogens require novel ideas for effective mitigation. Gennova’s m-RNA platform supported by DBT utilizes the advances in nucleic acid vaccine and delivery systems. This vaccine candidate that makes use of nanotechnology has shown promise to be effective in animal models. With the kind of capacities, Gennova has, I am confident that this vaccine candidate can be rapidly scaled up, once proven effective in human clinical trials.”

Speaking on the development, CEO of Gennova Biopharmaceuticals Ltd, Dr Sanjay Singh said, “Bold moves are necessary to create globally competitive and sustainable solutions. Gennova appreciates DBT- BIRAC's initiative, guidance, and financial support towards the development of mRNA based next-generation vaccine. Our partnership is poised towards creating an eco-system for cutting-edge technology, providing solution towards making a cost-effective vaccine that can reach to the masses in a pandemic situation like COVID-19.”

(With Inputs from PIB)