FACTBOX-Latest on the worldwide spread of coronavirus

* Eikon users, see MacroVitals cpurl://apps.cp./cms/?navid=1592404098 for a case tracker and summary of news. EUROPE * Germany's Foreign Ministry advised tourists against travelling to a batch of European destinations including Prague, Geneva, Dubrovnik and Corsica due to high coronavirus infection rates. * France's daily new COVID-19 infections rose by more than 8,500 for the third time in six days on Wednesday, with the disease spreading at its fastest pace since it emerged in the country.

AstraZeneca's suspension of global trials of its experimental coronavirus vaccine after an illness in a study subject in Britain has cast doubt on prospects for an early rollout of one of the most advanced COVID-19 vaccines in development.

DEATHS AND INFECTIONS * For an interactive graphic tracking the global spread, open https://tmsnrt.rs/3aIRuz7 in an external browser.

* For a U.S.-focused tracker with state-by-state and county map, open https://tmsnrt.rs/2w7hX9T in an external browser. * Eikon users, see MacroVitals cpurl://apps.cp./cms/?navid=1592404098 for a case tracker and summary of news.

EUROPE * Germany's Foreign Ministry advised tourists against travelling to a batch of European destinations including Prague, Geneva, Dubrovnik and Corsica due to high coronavirus infection rates.

* France's daily new COVID-19 infections rose by more than 8,500 for the third time in six days on Wednesday, with the disease spreading at its fastest pace since it emerged in the country. * Spanish bar, restaurant and nightclub owners gathered in central Madrid to ask the government for tax cuts and support.

* Georgia has banned weddings and other types of public ceremony from Sept. 10 and postponed theatre and cinema openings. ASIA-PACIFIC

* Indonesia's capital will reinstate widespread social restrictions as cases and deaths increase and hospitals fill up, its governor said. AMERICAS

* U.S. Senate leaders held onto their radically different positions on what is needed to address the continuing fallout from the coronavirus pandemic, one day before a vote on a modest Republican bill that appeared destined for defeat. * The U.S. government is set to end enhanced screening of some international passengers for COVID-19 and drop requirements that travelers coming from the targeted countries arrive at 15 designated U.S. airports.

* The governor of Brazil's São Paulo state said that Phase 3 clinical trials of a potential COVID-19 vaccine developed by China's Sinovac Biotech Ltd have shown promising results and it may be available to Brazilians as early as December. * Mexico's finance minister said the government's 2021 growth estimate of 4.6% was not over-optimistic, and did not depend on the development of a vaccine.

MIDDLE EAST AND AFRICA * A deal signed by the Kenyan government to lease medical equipment in a $580 million deal was a "criminal enterprise" that flooded hospitals with overpriced, unnecessary equipment, a senate committee said in a report.

MEDICAL DEVELOPMENTS * The European Commission said it had entered final-stage talks with BioNTech-Pfizer to buy up to 300 million doses of a potential vaccine.

* Twenty-six scientists, most of them working at universities in Italy, have signed an open letter questioning the reliability of the data presented in the early-stage trial results of the Russian COVID-19 vaccine, named "Sputnik-V". ECONOMIC IMPACT

* Concentrations of greenhouse gases in the atmosphere hit a record high, a U.N. report showed, as the economic slowdown had little long-term effect. * The stalling of a global economic recovery is leading to a fresh build-up of oil supplies, pushing traders to book tankers to store millions of barrels of crude oil and refined fuels at sea again.

(Compiled by Sarah Morland; Editing by Kevin Liffey and Maju Samuel)