The saffron party also said the charges against Akbar needed to be investigated thoroughly.
"As far as I know, there are five to six women professionals who have openly narrated how they were sexually attacked by M J Akbar. The details are worrisome and serious. Hence, I demand that he should be removed from his post immediately," Sena spokesperson Manisha Kayande said.
"Prime Minister Narendra Modi frequently talks about 'Beti Bachao-Beti Padhao'. Hence, in order to maintain his own image, Modi should remove Akbar from his post," she added.
"Let there be a proper investigation into the accusations against him. If Akbar comes out clean, he can be reinstated in the cabinet," the Sena MLC said.
The legislator also took a dig at the Maharashtra State Commission for Women, saying it was not doing its job properly.
"The chairperson of the commission has been a long-standing member of the BJP. She (Vijaya Rahatkar) only issues notices and selectively gives clean chits. She is certainly not using her judicial powers," Kayande said.
As the #MeToo campaign gathered momentum in India, several women journalists have come out and accused Akbar, a former newspaper editor and now the Union minister of state for external affairs, of sexually harassing them during his stint as a journalist.
(With inputs from agencies.)