Tackling Epilepsy: The Gender Hormone Connection

About 50 million people globally have epilepsy, half of whom are women. Women experience epilepsy differently due to fluctuating hormones, which affect seizure frequency at various life stages. Researchers emphasize the need for tailored therapies considering women’s hormonal changes to better manage epilepsy and improve quality of life.

PTI | Brisbane | Updated: 13-06-2024 15:18 IST | Created: 13-06-2024 15:18 IST
Tackling Epilepsy: The Gender Hormone Connection
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Brisbane, Jun 13 (The Conversation) – Around 50 million individuals worldwide are living with epilepsy, with half being women. Traditionally, treatments have been the same for both men and women, an approach that overlooks the unique ways women's fluctuating hormones impact seizure frequency at different life stages. Recent research underscores the necessity of tailoring therapies to women's hormonal profiles.

Understanding epilepsy involves recognizing the brain's delicate electrical balance. In people without epilepsy, signals on neurons finely balance excitation and inhibition. However, epilepsy disrupts this balance, resulting in unpredictable bursts of electrical activity that cause seizures akin to sudden earthquakes.

Hormonal variations, especially with oestrogen and progesterone, play a significant role in epilepsy. Oestrogen increases electrical activity, while progesterone decreases it. Imbalances during menstruation or menopause can lead to changes in seizure frequency. Researchers call for urgent studies to explore how hormone fluctuations affect epilepsy and to create better treatments for women. Without this focus, many may not receive adequate care for their condition.

(This story has not been edited by Devdiscourse staff and is auto-generated from a syndicated feed.)

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