The seizure was made late on November 28 night and the arrested people hail from Amravati in the Vidarbha region of eastern Maharashtra, D S Swami, Deputy Commissioner of Police (Zone I) told a news conference.
He said acting on a tip-off that some people involved in wildlife trade were coming near the Global Park on way to Mumbra town, a police team kept a vigil and intercepted the car in which they were travelling.
A search of the car revealed its occupants had concealed different kinds of deer horns and a skin of the protected animal in the vehicle, he said.
An offence under the Protection of Wildlife Act has been registered against the trio, identified by the police as Mohammad Tousif Israel Saudagar (27), Shaikh Tousif Sheikh Nasir (22) and Rizvan Ahmed Rajik Ahmed (23).
(With inputs from agencies.)