FACTBOX-Latest on the worldwide spread of the coronavirus

* Eikon users, see MacroVitals (cpurl://apps.cp./cms/?navid=1592404098) for a case tracker and a summary of developments. EUROPE * Britain will switch to the Apple and Google model for its COVID-19 test-and-trace app, the government said. * Russia has revised steeply higher, to nearly 500, the number of medical workers who have died after contracting COVID-19.

The World Health Organization hopes hundreds of millions of doses of coronavirus vaccine can be produced this year and 2 billion doses by the end of 2021, its chief scientist said. DEATHS AND INFECTIONS

* More than 8.38 million people have been reported to be infected by the novel coronavirus globally and 448,547​ have died, a Reuters tally showed as of 1600 GMT on Thursday. * For an interactive graphic tracking the global spread, open https://tmsnrt.rs/3aIRuz7 in an external browser.

* For a U.S.-focused tracker with state-by-state and county map, open https://tmsnrt.rs/2w7hX9T in an external browser. * Eikon users, see MacroVitals (cpurl://apps.cp./cms/?navid=1592404098) for a case tracker and a summary of developments.

EUROPE * Britain will switch to the Apple and Google model for its COVID-19 test-and-trace app, the government said.

* Russia has revised steeply higher, to nearly 500, the number of medical workers who have died after contracting COVID-19. * Slovenia will introduce an obligatory 14-day quarantine from Friday for most people coming from Serbia, Bosnia and Kosovo, the government said.

AMERICAS * New York Governor Andrew Cuomo slammed the federal government's handling of the epidemic and said he was considering a quarantine for travellers from Florida.

* California ordered residents to wear masks at nearly all times outside the home. * The coronavirus is threatening to hamstring Mexico's fight against some of its most vicious drug gangs.

ASIA-PACIFIC * Indonesia's central bank came under pressure from lawmakers to escalate its response to the economic fallout, even as it cut its benchmark interest rate to a two-year low.

* Beijing has brought its latest coronavirus outbreak under control, a Chinese medical expert said. * China has found the trading sections for meat and seafood in Beijing's wholesale food market to be severely contaminated with the new coronavirus, officials said.

MIDDLE EAST AND AFRICA * Madagascar has announced a stimulus package offering close to a million small businesses secure loans at below market rates.

* The new coronavirus pandemic hit Cape Town much earlier than previously assumed, a senior health official said. MEDICAL DEVELOPMENTS

* Large multi-country trials of the combination HIV drug lopinavir/ritonavir to treat COVID-19 have recruited thousands of patients and the WHO is now looking at interim data, the UN agency's chief scientist said. * The European Commission is in advanced talks with pharmaceutical giant Johnson & Johnson to reserve or buy up-front doses of its COVID-19 vaccine under development, two officials familiar with the talks told Reuters.

* Roche's rheumatoid arthritis drug Actemra failed to help patients with early-stage COVID-19 pneumonia in an Italian study. ECONOMIC FALLOUT

* Global stocks drifted lower as an increase in new coronavirus cases in some U.S. states and China dimmed hopes of a swift world economic comeback from the pandemic. * A second wave of COVID-19 and another round of sweeping lockdowns could have a "very serious" impact on the Canadian economy and must be avoided, Bank of Canada Deputy Governor Lawrence Schembri said.

* South Africa's bad debts could hit 10% of bank lending this year, its banking association director said. * The number of Americans filing for unemployment benefits fell last week, but the pace of decline has stalled amid a second wave of layoffs.

* Colombia's economy contracted 20.06% in April versus the same month last year, its largest fall on record, the government's statistics agency said. (Compiled by Linda Pasquini and Devika Syamnath, Editing by Tomasz Janowski and Maju Samuel)