Left Menu
Development News Edition

Study focuses on executive function in women post menopause

A recent study indicates that an assessment of anxiety and depression symptoms in women who have undergone surgical menopause for cancer risk reduction or RRSO may help in finding ways to ease cognitive distress in them.

Study focuses on executive function in women post menopause
Representative image. Image Credit: ANI

A recent study indicates that an assessment of anxiety and depression symptoms in women who have undergone surgical menopause for cancer risk reduction or RRSO may help in finding ways to ease cognitive distress in them. The novel study was published in the journal Menopause.

Researchers, including Neill Epperson of the University of Colorado Anschutz Medical Campus, remotely collected extensive cognitive data from women across the nation. 552 women who are BRCA1 and BRCA2 mutation carriers and have undergone RRSO completed the assessments, which measured executive function (a cognitive process that allows individuals to manage information in a planful versus reactive manner), exposure to early life stress, and mood symptoms. Results show that adverse childhood experiences (ACE) were associated with more severe symptoms of executive dysfunction and worse performances on cognitive tasks post-surgical menopause. Changes in mood, such as anxiety and depressive symptoms, partially mediated ACE associations on subjective and objective measures of executive function. These findings indicate that assessing the history of childhood adversity and current anxiety and depression symptoms may help to identify women who will experience executive cognitive complaints after surgical menopause.

This research emphasizes the importance of considering psychological state during other medical procedures. "We can't change the past for women who have experienced serious childhood adversities such as abuse, neglect, divorce, parental substance abuse, or exposure to domestic violence, but we can identify a patient population that is easily assessed for these ACEs as well as current negative mood symptoms," said Epperson, study lead investigator and professor and chair of psychiatry at the University of Colorado School of Medicine. "Our hope is that assessment of childhood adversity and history of depression and anxiety would become part of the pre-surgical risk-benefit discussion between patients and their doctors." "Many women have told me over the years that their doctor did not warn them about the potential brain effects of undergoing surgical menopause. While these women may have made the same decision regarding surgery given its life-preserving benefits, they indicated that they wish they had been informed about the potential cognitive and mood effects so that they could be prepared and seek treatment sooner," says Epperson. (ANI)

(This story has not been edited by Devdiscourse staff and is auto-generated from a syndicated feed.)

Download The Devdiscourse News App for Latest News.



Coronavirus lockdowns to speed up long-pending revamping of supply chains

With millions of production lines impacted, business disruptions to some extent are unavoidable and the lessons learned from this turbulence will leave an everlasting impact on both global and local levels of supply chains....

COVID 19 to catalyze the redefinition of urban planning and sustainability

Until now the urban planning was focused on mitigation to natural disastrous, climate change, pollution, chronic illness and lifestyle diseases. However, the global pandemic of novel coronavirus is going to change the whole narrative of urb...

Ebola to COVID 19: Has Geopolitics prevailed over Professionalism in WHO

World Health Organization WHO is perceived as one of the most professional bodies of the United Nations. However, the role of WHO has come under question in handling outbreak two deadly diseases Ebola Viral Disease EVD and novel Coronaviru...

Trade War, COVID 19 and Beyond: How Pandemic is defining a New World Order

While we are confined in our homes, the world is changing faster than ever. Geopolitics in the time pandemic is defining a new world order. The transformation is happening in almost all the walks of life but the million-dollar question is ...


Latest News

Pedro reveals angst of separation from children due to virus

Chelsea winger Pedro admits he is finding it hard separated from his children due to the coronavirus lockdown. Pedros kids are back in Spain and the 32-year-old is unable to go home to see his family because of the travel restrictions impos...

With one more case, number of coronavirus cases in MP is 34

The number of coronavirus cases in Madhya Pradesh increased by one to 34 on Saturday with a Border Security Force BSF officer testing positive for the infection. The officers wife had returned from abroad recently, said coronavirus nodal of...

IAS officer Peeyush Kumar appointed as Nodal Officer for supervising COVID-19 quarantine camps in Andhra Pradesh

Andhra Pradesh Government has appointed IAS officer Peeyush Kumar as the Nodal Officer at State Level for supervising COVID-19 healthcare quarantine camps set-up in the various districts of the state.The state government has constituted a f...

Covid-19 death toll rises to 6 in Maharashtra

Mumbai Maharashtra India, Mar 28 ANIThe number of deaths of coronavirus patients in Maharashtra rose to six, officials said on Saturday. Total 6 patients 4 from Mumbai who tested positive for COVID-19 have passed away in the state, Brihanmu...

Give Feedback